Produced in the pancreas, insulin is the hormone famous for its role in maintaining the delicate balance of blood sugar levels. It works by helping your body turn glucose into stored energy and then signaling for the release of that energy when your sugar levels run low. Insulin resistance, when the body does not react properly to the hormone, has implications in many areas of health, including skin. Insufficient production or the malfunctioning of insulin can lead to diabetes, signs of which often appear in the skin as dark patches, skin infections, and acne.